A traditional problem, discussed here previously, is that if you’ve disabled third-party cookies in your browser, many works (particularly Twine and Adventuron, but other systems too) fail with cryptic error messages or just with a blank screen.
The easiest current workaround I know of for that one (in desktop Firefox at least) is to right-click over the playing area, and choose This Frame > Show Only This Frame.
(Anyway, this is all a massive derail from the original poster’s question. Maybe it should be split to its own topic.)