Non-Inform Z-Machine game engines?

Anyway, back to the original premise @FredMSloniker : if you want to work in a system that

  • is available today
  • produces comfortably playable C64 binaries
  • has contemporary support from contemporary enthusiasts and system-minders

your top choices are probably ZIL and DAAD. DAAD isn’t Z-Machine but it is a multiplatform system.