Well, what the question says.
Of course switching it on in Debug mode means we can’t see rule names, which is bad for bug-hunting.
I realized, though, I’d been assuming it had no drawbacks in release.
Similarly, I’m curious about OMIT_UNUSED_ROUTINES’s possible ill effects on release builds, as it’s done a neat job of keeping some of my projects in z-machine range. It doesn’t feel like there should be any, but you never know.