I’ve said all this before, but having used left/right/forward/back in Lady Thalia 2 I can’t say I recommend it. Players didn’t actually complain about it*, but it was a huge headache on the programming end to have to keep track of where players were coming from and opened up a lot of extra opportunities for bugs. I don’t exactly regret doing it, because I still think navigating a private home with compass directions would have been distractingly artificial in a choice-based game, but I didn’t have a whole lot of fun with it.
[*] Though this may have been because it wasn’t a parser game; n/e/w/s is so entrenched in the parser-game-playing part of my brain that I struggle a bit even with stuff like nautical directions, so I can definitely imagine the reaction would be worse if it had been.