What is the trigger for changing the link? And do you want to change the link text, the passage it goes to, or both? Do you want any visible indicator of this change? Such as fading from one to the other?
More information is necessary to answer this question, but I’ll say it’s quite possible. Take a look at the <<replace>> macro, and if you still have questions, just provide the information requested above so we have a better idea what you’re looking to accomplish.
Further to HiEi’s advice regarding the <<replace>> macro, and their request for further information…
A link replacing example would look something like the following, except I’m using a <<button>> macro to simulate your ‘event’ handling system, so I can delay the execution of the <<replace>> macro call. I’m also using Custom Styling markup to define the #link identified area the original link is being shown in.